BDBM50020224 1-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-4-methyl-piperazine::CHEMBL70887
SMILES CN1CCN(CC1)[C@@H]1C[C@H](c2ccc(F)cc12)c1ccc(F)cc1
InChI Key InChIKey=BOFPIRRSGDHUCZ-AZUAARDMSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50020224
Affinity DataIC50: 31nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibition of [3H]dopamine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck
Curated by ChEMBL
H. Lundbeck
Curated by ChEMBL
Affinity DataIC50: 9.30nMAssay Description:Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of [3H]norepinephrine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:In vitro inhibition of [3H]5-HT transporter uptake in rat brain synaptosomesMore data for this Ligand-Target Pair