BDBM50020247 1-(2-{4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-3-methyl-imidazolidin-2-one::CHEMBL306960

SMILES CN1CCN(CCN2CCN(CC2)[C@@H]2C[C@H](c3ccc(F)cc23)c2ccc(F)cc2)C1=O

InChI Key InChIKey=OJVLTRBLPKFAOC-LADGPHEKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50020247   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020247(1-(2-{4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  38nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020247(1-(2-{4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50020247(1-(2-{4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed