BDBM50020270 (RS)-1-(4-Chloro-phenyl)-3-[2-oxo-1-(2-oxo-2-pyrrolidin-1-yl-ethyl)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-urea::1-(4-Chloro-phenyl)-3-[2-oxo-1-(2-oxo-2-pyrrolidin-1-yl-ethyl)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-urea::CHEMBL445095

SMILES Clc1ccc(NC(=O)NC2N=C(c3ccccc3)c3ccccc3N(CC(=O)N3CCCC3)C2=O)cc1

InChI Key InChIKey=ZBDUNBHRAGZXHV-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50020270   

TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020270((RS)-1-(4-Chloro-phenyl)-3-[2-oxo-1-(2-oxo-2-pyrro...)
Affinity DataIC50:  0.5nMAssay Description:Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.More data for this Ligand-Target Pair
In DepthDetails Article
TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50020270((RS)-1-(4-Chloro-phenyl)-3-[2-oxo-1-(2-oxo-2-pyrro...)
Affinity DataIC50:  520nMAssay Description:Ability to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreas.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020270((RS)-1-(4-Chloro-phenyl)-3-[2-oxo-1-(2-oxo-2-pyrro...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020270((RS)-1-(4-Chloro-phenyl)-3-[2-oxo-1-(2-oxo-2-pyrro...)
Affinity DataIC50:  0.280nMAssay Description:Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020270((RS)-1-(4-Chloro-phenyl)-3-[2-oxo-1-(2-oxo-2-pyrro...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of 125 I-gastrin from gastrin receptor of guinea pig gastric glandsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50020270((RS)-1-(4-Chloro-phenyl)-3-[2-oxo-1-(2-oxo-2-pyrro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020270((RS)-1-(4-Chloro-phenyl)-3-[2-oxo-1-(2-oxo-2-pyrro...)
Affinity DataIC50:  0.280nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type B receptor of guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50020270((RS)-1-(4-Chloro-phenyl)-3-[2-oxo-1-(2-oxo-2-pyrro...)
Affinity DataIC50:  520nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed