BDBM50020447 CHEMBL3290123

SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1C(=O)Nc1cnc(Nc2cccc(N)c2)nc1

InChI Key InChIKey=FCXFBAVJAPHCTG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50020447   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50020447(CHEMBL3290123)
Affinity DataIC50:  14nMAssay Description:Inhibition of Btk (unknown origin) after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50020447(CHEMBL3290123)
Affinity DataIC50:  42nMAssay Description:Inhibition of wild type N-terminal GST tagged BTK (unknown origin) (2 to 659 residues) expressed in sf21 insect cell using TK as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50020447(CHEMBL3290123)
Affinity DataIC50:  15nMAssay Description:Inhibition of wild type N-terminal GST tagged BLK (unknown origin) (1 to 505 residues) expressed in sf21 insect cell using TK as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50020447(CHEMBL3290123)
Affinity DataIC50:  5nMAssay Description:Inhibition of Lck (unknown origin) after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed