BDBM50020586 CHEMBL3290440

SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2cc(CCC(C)C)c(O)c(OC)c2)cc(CCC(C)C)c1O

InChI Key InChIKey=DYJZWLPHCDNBGR-UTLPMFLDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020586   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Jena

Curated by ChEMBL
LigandPNGBDBM50020586(CHEMBL3290440)
Affinity DataIC50:  8.02E+4nMAssay Description:Inhibition of 5-LO in human neutrophils using arachidonic acid as substrate preincubated for 15 mins measured after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Jena

Curated by ChEMBL
LigandPNGBDBM50020586(CHEMBL3290440)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli Bl21 (DE3) using arachidonic acid as substrate preincubated for 10 mins measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed