BDBM50020919 CHEMBL3287282

SMILES OC(=O)c1cccc(n1)-c1ccc2CCC\C(=N/Nc3nc4ccccc4s3)c2c1

InChI Key InChIKey=ZGERKAMDOWOUTN-NLRVBDNBSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50020919   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50020919(CHEMBL3287282)
Affinity DataIC50:  20nMAssay Description:Displacement of 26-mer BIMBH3 peptide from GST-tagged Bcl-Xl (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50020919(CHEMBL3287282)
Affinity DataIC50:  21nMAssay Description:Inhibition of GST-tagged Bcl-xL (unknown origin) measured after 1 hr incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50020919(CHEMBL3287282)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at Bcl-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed