BDBM50021900 6-(3,4-Dichloro-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline;C4H4O4::CHEMBL287474

SMILES Clc1ccc(cc1Cl)[C@@H]1CN2CCC[C@@H]2c2ccccc12

InChI Key InChIKey=MKONYSHULTYBAP-MAUKXSAKSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50021900   

TargetTransporter(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021900(6-(3,4-Dichloro-phenyl)-1,2,3,5,6,10b-hexahydro-py...)
Affinity DataKi:  0.680nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021900(6-(3,4-Dichloro-phenyl)-1,2,3,5,6,10b-hexahydro-py...)
Affinity DataKi:  0.990nMAssay Description:Inhibition of the uptake of tritiated dopamine (DA) in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021900(6-(3,4-Dichloro-phenyl)-1,2,3,5,6,10b-hexahydro-py...)
Affinity DataKi:  1.80nMAssay Description:Inhibition the uptake of tritiated serotonin (5-HT) by the serotonin transporter SERT in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021900(6-(3,4-Dichloro-phenyl)-1,2,3,5,6,10b-hexahydro-py...)
Affinity DataKi:  465nMAssay Description:Binding affinity towards serotonin S1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021900(6-(3,4-Dichloro-phenyl)-1,2,3,5,6,10b-hexahydro-py...)
Affinity DataKi:  990nMAssay Description:Binding affinity towards alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed