BDBM50021981 CHEMBL3297865

SMILES COc1ccc(cc1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=UXQGJOGBIHMDHQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50021981   

TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50:  1.20E+4nMAssay Description:Irreversible inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of human recombinant MAGL using 4-NPA substrate incubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50:  1.22E+4nMAssay Description:Irreversible inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate preincubated for 60 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50:  8.60E+3nMAssay Description:Competitive inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50021981(CHEMBL3297865)
Affinity DataIC50:  1.27E+4nMAssay Description:Irreversible inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed