BDBM50022279 3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)-benzyl]-1-heptyl-urea::CHEMBL277986::CL-277082

SMILES CCCCCCCN(Cc1ccc(CC(C)(C)C)cc1)C(=O)Nc1ccc(F)cc1F

InChI Key InChIKey=QKJLDOBXDUVGEE-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50022279   

TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50022279(3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)...)
Affinity DataIC50:  180nMAssay Description:Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50022279(3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)...)
Affinity DataIC50:  900nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50022279(3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)...)
Affinity DataIC50:  180nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Eisai

Curated by ChEMBL
LigandPNGBDBM50022279(3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dimethyl-propyl)...)
Affinity DataIC50:  900nMAssay Description:Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed