BDBM50022510 Boc-Phe-His-Leu-CF3-Ile-Amp::CHEMBL154795

SMILES CC[C@H](C)[C@H](NC(=O)C(F)(F)C(=O)C(CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NCc1ccccn1

InChI Key InChIKey=YJEITIRWMUEULI-WNTFFZHHSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50022510   

TargetPepsin A-5(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)
Affinity DataIC50:  4.20nMpH: 3.1Assay Description:Inhibition of human pepsin at pH 2.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)
Affinity DataIC50:  4nMpH: 3.2Assay Description:Inhibition of bovine cathepsin D at pH 3.1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)
Affinity DataIC50:  1.40nMpH: 6.0Assay Description:Inhibition of human renin at pH 6.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPepsin A-5(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)
Affinity DataIC50:  6nMpH: 3.1Assay Description:Inhibition of bovine cathepsin D at pH 3.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)
Affinity DataIC50:  1.70nMpH: 3.2Assay Description:Inhibition of human pepsin at pH 3.1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50022510(Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795)
Affinity DataIC50:  1nMpH: 7.0Assay Description:Inhibition of human renin at pH 7.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed