BDBM50022775 (m-Hydroxyphenyl)trimethylammonium dimethylcarbamate::3-Trimethylammoniumphenyl N,N-dimethylcarbamate::3-[(dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium::CHEMBL211471::CHEMBL278020::Eustigmin::Eustigmine::NEOSTIGMINE::Neostigmine (2)::Prostigmine::Vagostigmine::m-Trimethylammoniumphenyldimethylcarbamate

SMILES CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C

InChI Key InChIKey=ALWKGYPQUAPLQC-UHFFFAOYSA-N

Data  3 KI  57 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50022775   

TargetCholinesterase(Homo sapiens (Human))
Comsats Institute of Information Technology

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition assay using AChE and BuChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
Comsats Institute of Information Technology

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  800nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
Comsats Institute of Information Technology

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  4.91E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after 15 mins by Ellman's me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Equus caballus (Horse))
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  4.96E+4nMAssay Description:Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Comsats Institute of Information Technology

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  2.61E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after 15 mins by Ellman's me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
Comsats Institute of Information Technology

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Equus caballus (Horse))
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  70nMAssay Description:Inhibition of equine serum BChE using butylthiocholine iodide as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Comsats Institute of Information Technology

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Equus caballus (Horse))
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  2.93E+3nMAssay Description:Inhibition of equine BuChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  9.27E+4nMAssay Description:Inhibition of horse serum BChE incubated for 5 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Government College Women University

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  160nMAssay Description:Inhibition of equine BChE using acetylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCholinesterase(Homo sapiens (Human))
Comsats Institute of Information Technology

LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human plasma BChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank