BDBM50023033 CHEMBL3298367

SMILES O=C(Nc1cnn(Cc2ccccc2)c1)c1n[nH]c2CC3(CCOC3)CCc12

InChI Key InChIKey=DGTFAVKOOZFPJL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50023033   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50023033(CHEMBL3298367)
Affinity DataKi:  42nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50023033(CHEMBL3298367)
Affinity DataKi:  55nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50023033(CHEMBL3298367)
Affinity DataKi: >5.70E+3nMAssay Description:Inhibition of human His-tagged full length AURKA using kemptide peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed