BDBM50023589 CHEMBL3355573

SMILES [H][C@@]1(CC[C@@H](CC1)NCc1ncc2OCC(=O)Nc2n1)[C@@H](N)Cn1c2cc(F)ccc2ncc1=O

InChI Key InChIKey=PIVJTBXDGKAQQI-BPUTZDHNSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50023589   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50023589(CHEMBL3355573)
Affinity DataIC50: >3.33E+5nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50023589(CHEMBL3355573)
Affinity DataIC50: >3.33E+5nMAssay Description:Inhibition of potassium channel IKs (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50023589(CHEMBL3355573)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of potassium channel Kv1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50023589(CHEMBL3355573)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of potassium channel HCN4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50023589(CHEMBL3355573)
Affinity DataIC50: >3.33E+5nMAssay Description:Inhibition of potassium channel Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50023589(CHEMBL3355573)
Affinity DataIC50: >3.33E+5nMAssay Description:Inhibition of potassium channel Cav1.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50023589(CHEMBL3355573)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of potassium channel Cav3.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50023589(CHEMBL3355573)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of potassium channel Kv4.3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed