BDBM50023893 4-(Adamantan-1-ylcarbamoyl)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-amino]-benzoylamino}-butyric acid::CHEMBL45572

SMILES Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)NC(CCC(=O)N[C@]34C[C@H]5C[C@H](C[C@H](C5)C3)C4)C(O)=O)cnc2n1

InChI Key InChIKey=IXWQBJKCIWPCJL-GXBINLNZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023893   

TargetDihydrofolate reductase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50023893(4-(Adamantan-1-ylcarbamoyl)-2-{4-[(2,4-diamino-pte...)
Affinity DataIC50:  100nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed