BDBM50023902 2-{4-[(2-Amino-4-oxo-1,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid (DDF)::2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid::CHEMBL22973::TCMDC-132046

SMILES Nc1nc2ccc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=UQFCLENKCDVITL-INIZCTEOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50023902   

TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50023902(2-{4-[(2-Amino-4-oxo-1,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50:  1.00E+4nMAssay Description:Evaluated for the inhibition of thymidylate synthase in permeabilised L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50023902(2-{4-[(2-Amino-4-oxo-1,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50:  1.00E+4nMAssay Description:Evaluated for the inhibition of thymidylate synthase in permeabilised L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50023902(2-{4-[(2-Amino-4-oxo-1,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50:  2.70E+3nMAssay Description:Ability to inhibit thymidylate synthase derived from human leukemia K562 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed