BDBM50023908 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-ethynyl-amino]-benzoylamino}-pentanedioic acid::CHEMBL161567

SMILES Nc1nc(N)c2nc(CN(C#C)c3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)cnc2n1

InChI Key InChIKey=GVOLBCKIYMYHBJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023908   

TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50023908(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-ethynyl-am...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity against human thymidylate synthase derived either from HeLa or KB cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed