BDBM50025098 CHEMBL332551

SMILES Nc1nc(c(O)[nH]1)C1=C2C(=Nc3ccccc23)C(=O)NCC1

InChI Key InChIKey=RZEPRPGFGRQXDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025098   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50025098(CHEMBL332551)
Affinity DataIC50:  470nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50025098(CHEMBL332551)
Affinity DataIC50:  234nMAssay Description:Inhibition of human CHK1 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Michigan State University

Curated by ChEMBL
LigandPNGBDBM50025098(CHEMBL332551)
Affinity DataIC50:  8nMAssay Description:Inhibition of human Chk2 using STK1 as substrate after 10 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed