BDBM50026259 CHEMBL3359023

SMILES [H][C@@]12C[C@@H](C[C@]1([H])CN(C2)C(=O)Nc1cc(C)ncc1C(O)=O)c1ccccc1C(F)(F)F

InChI Key InChIKey=KGAYRJHUIIQQLX-QKDCVEJESA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50026259   

TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50026259(CHEMBL3359023)
Affinity DataIC50:  0.235nMAssay Description:Antagonist activity at maltose binding protein-tagged RBP4 (unknown origin) expressed in Escherichia coli assessed as inhibition of retinol-induced p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50026259(CHEMBL3359023)
Affinity DataIC50:  24nMAssay Description:Displacement of [3H]retinol from biotinylated human RBP4 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50026259(CHEMBL3359023)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50026259(CHEMBL3359023)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50026259(CHEMBL3359023)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Albany Molecular Research

Curated by ChEMBL
LigandPNGBDBM50026259(CHEMBL3359023)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed