BDBM50026673 CHEMBL3335387

SMILES CCN1CCN(CC(=O)Nc2cc(Oc3ccc4n(C)c(Nc5cc(ccc5F)C(F)(F)F)nc4c3)ccn2)CC1

InChI Key InChIKey=CXXTWUWDVIYTID-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50026673   

TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50026673(CHEMBL3335387)
Affinity DataIC50: <10nMAssay Description:Inhibition of VEGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50026673(CHEMBL3335387)
Affinity DataIC50: <10nMAssay Description:Inhibition of PDGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50026673(CHEMBL3335387)
Affinity DataIC50: <10nMAssay Description:Inhibition of CSF1R kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50026673(CHEMBL3335387)
Affinity DataEC50:  100nMAssay Description:Inhibition of BRAF (unknown origin)-mediated ERK phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50026673(CHEMBL3335387)
Affinity DataIC50:  240nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50026673(CHEMBL3335387)
Affinity DataIC50: <10nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50026673(CHEMBL3335387)
Affinity DataIC50:  6nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed