BDBM50026952 (cis) [3-(3,4-Dichloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]-dimethyl-amine(LR 5182)::CHEMBL322067::LR 5182::[(2R,3S)-3-(3,4-Dichloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]-dimethyl-amine
SMILES CN(C)C[C@@H]1C2CCC(CC2)[C@@H]1c1ccc(Cl)c(Cl)c1
InChI Key InChIKey=JOQQHMGSIKNGAF-HLFYOVGASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50026952
Affinity DataKi: 7.20nMAssay Description:In vitro inhibition of [3H]-NE re-uptake into synaptosomeMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Lundbeck Ais
Curated by PDSP Ki Database
Lundbeck Ais
Curated by PDSP Ki Database
Affinity DataKi: 44nMAssay Description:Displacement of [3H]-WIN-35,428 from Dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Lundbeck Ais
Curated by PDSP Ki Database
Lundbeck Ais
Curated by PDSP Ki Database
Affinity DataKi: 57nMAssay Description:Displacement of [3H]-WIN-35,428 from Dopamine transporterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Lundbeck Ais
Curated by PDSP Ki Database
Lundbeck Ais
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Lundbeck Ais
Curated by PDSP Ki Database
Lundbeck Ais
Curated by PDSP Ki Database
Affinity DataIC50: 51nMAssay Description:Effect on synaptosomal uptake inhibition of 5-hydroxytryptamine (5-HT)More data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:In vitro ability of compound to inhibit 5-HT re-uptake of radiolabelled [3H]-tritium trasmitter into synaptosomeMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of [3H]-NE re-uptake into synaptosomeMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Effect of compound on synaptosomal uptake inhibition of Dopamine (DA)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:In vitro inhibition of DA re-uptake into synaptosomeMore data for this Ligand-Target Pair