BDBM50027205 5-[4-Hydroxy-4-(4-methoxy-phenyl)-piperidin-1-yl]-2,2-diphenyl-pentanenitrile::CHEMBL141713

SMILES COc1ccc(cc1)C1(O)CCN(CCCC(C#N)(c2ccccc2)c2ccccc2)CC1

InChI Key InChIKey=FFRLOIAKURWWBT-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50027205   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50027205(5-[4-Hydroxy-4-(4-methoxy-phenyl)-piperidin-1-yl]-...)
Affinity DataKi:  347nMAssay Description:Inhibition of [125I]-MIP-1 alpha binding to recombinant human C-C chemokine receptor type 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor homolog US28(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM50027205(5-[4-Hydroxy-4-(4-methoxy-phenyl)-piperidin-1-yl]-...)
Affinity DataEC50:  2.88E+4nMAssay Description:Effective concentration against US28-mediated inositol phosphate production in COS-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor homolog US28(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM50027205(5-[4-Hydroxy-4-(4-methoxy-phenyl)-piperidin-1-yl]-...)
Affinity DataIC50:  7.24E+4nMAssay Description:Inhibitory concentration against chemokine receptor US28 expressed in COS-7 cells using [125I]-CCL5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed