BDBM500277 N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-2-((2-isocyanoquinolin-6- yl)methyl)isonicotinamide::US11021463, Example 131

SMILES Cc1cc(N)nc(F)c1CNC(=O)c1ccnc(Cc2ccc3nc(ccc3c2)C#N)c1

InChI Key InChIKey=YAJOVNHXSYCRPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 500277   

TargetPlasma kallikrein(Homo sapiens (Human))
Attune Pharmaceuticals

US Patent
LigandPNGBDBM500277(N-((6-amino-2,4-dimethylpyridin-3- yl)methyl)-2-((...)
Affinity DataIC50: <100nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent