BDBM50028106 CHEMBL46945::diethyl 2-{4-[2-amino-4-oxo-3,4,5,6,7,8-hexahydropyrido[3,2-d]pyrimidin-6-ylmethyl(nitroso)amino]phenylcarboxamido}pentanedioate

SMILES CCOC(=O)CCC(NC(=O)c1ccc(cc1)N(CC1CCc2nc(N)[nH]c(=O)c2N1)N=O)C(=O)OCC

InChI Key InChIKey=ARYXVSBYFJYSSQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50028106   

TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028106(CHEMBL46945 | diethyl 2-{4-[2-amino-4-oxo-3,4,5,6,...)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of N5, 10-CH2-H4PteGlu and fixed dUMP (100 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028106(CHEMBL46945 | diethyl 2-{4-[2-amino-4-oxo-3,4,5,6,...)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of N5, 10-CH2-H4PteGlu and fixed dUMP (100 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed