BDBM50028601 1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL7617
SMILES CN1CCN(CC1)C1=Cc2ccccc2Cc2ccc(Cl)cc12
InChI Key InChIKey=SFRWZRKAHVGRFO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50028601
Affinity DataKi: 1nMAssay Description:Affinity was evaluated by inhibition of [3H]-spiperone binding to COS cells transfected with human dopamine D-4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Affinity was evaluated by inhibition of [3H]-spiperone binding to COS cells transfected with human dopamine D-2(long) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro binding affinity towards Dopamine receptor D2 in rat tissue homogenate using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Affinity was evaluated by inhibition of [125I]-LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Vanderbilt University
Curated by ChEMBL
Vanderbilt University
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Affinity of the compound was evaluated by inhibition of [125I]-LSD binding to NIH 3T3 cells transfected with cloned rat 5-hydroxytryptamine 2C recept...More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Affinity was evaluated by inhibition of [3H]-GR-65,630 binding to NG108-15 cell transfected with cloned rat 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Displacement of 3[H]spiroperidol from Dopamine receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair