BDBM50028868 CHEMBL41233::N-[2-(4-Amino-phenyl)-1-phenyl-ethyl]-2,2-diphenyl-acetamide

SMILES Nc1ccc(CC(NC(=O)C(c2ccccc2)c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=AKYQUIAWRGDGCP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50028868   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50028868(CHEMBL41233 | N-[2-(4-Amino-phenyl)-1-phenyl-ethyl...)
Affinity DataIC50:  900nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028868(CHEMBL41233 | N-[2-(4-Amino-phenyl)-1-phenyl-ethyl...)
Affinity DataIC50:  900nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50028868(CHEMBL41233 | N-[2-(4-Amino-phenyl)-1-phenyl-ethyl...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed