BDBM50029085 CHEBI:83405::CHEMBL525191::GDC-0879
SMILES OCCn1cc(c(n1)-c1ccncc1)-c1ccc2\C(CCc2c1)=N\O
InChI Key InChIKey=DEZZLWQELQORIU-RELWKKBWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50029085
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Albert Einstein College Of Medicine
Curated by ChEMBL
Albert Einstein College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.170nMAssay Description:Inhibition of BRAF V600E mutant in human MALME-3M cellsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Albert Einstein College Of Medicine
Curated by ChEMBL
Albert Einstein College Of Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of BRAF V600E mutant in human A375 cells assessed as reduction in ERK phosphorylation by ELISAMore data for this Ligand-Target Pair