BDBM50029232 CHEMBL134442::Pyridin-4-yl-acetic acid (3R,6R)-3,6,8,8-tetramethyl-octahydro-3a,7-methano-azulen-6-yl ester

SMILES C[C@@H]1CCC2C(C)(C)C3CC12CC[C@@]3(C)OC(=O)Cc1ccncc1

InChI Key InChIKey=DPHKDPSHQYZTCI-NAYOJDKUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029232   

TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029232(CHEMBL134442 | Pyridin-4-yl-acetic acid (3R,6R)-3,...)
Affinity DataIC50:  440nMAssay Description:Tested for inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029232(CHEMBL134442 | Pyridin-4-yl-acetic acid (3R,6R)-3,...)
Affinity DataIC50:  52nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029232(CHEMBL134442 | Pyridin-4-yl-acetic acid (3R,6R)-3,...)
Affinity DataIC50:  270nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed