BDBM50029238 CHEMBL132072::Pyridin-4-yl-acetic acid (S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester

SMILES C[C@H]1C2CC(CC1OC(=O)Cc1ccncc1)C2(C)C

InChI Key InChIKey=FYHFPSGWNXSFBI-WXPVAWKNSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029238   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  14nMAssay Description:Tested for inhibition of human testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  120nMAssay Description:Tested for inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of rat testicular C17,20-LyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  5nMAssay Description:Tested for inhibition of human testicular C17,20-Lyase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Crc Laboratory

Curated by ChEMBL
LigandPNGBDBM50029238(CHEMBL132072 | Pyridin-4-yl-acetic acid (S)-2,6,6-...)
Affinity DataIC50:  260nMAssay Description:Inhibition of rat testicular Steroid 17-alpha-hydroxylase/17,20 lyaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed