BDBM50029418 CHEMBL275195::[4-(2,4-Dimethoxy-phenyl)-4H-benzo[b]pyrrolo[1,2-d][1,4]thiazin-1-ylmethyl]-dimethyl-amine
SMILES COc1ccc(C2Sc3ccccc3-n3c(CN(C)C)ccc23)c(OC)c1
InChI Key InChIKey=ICMCIDYUTSXGGO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50029418
Affinity DataKi: 56nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Calcium antagonistic activity by measuring [3H]-nitrendipine displacement from rat heart L-type [Ca2+] channelMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena
Curated by ChEMBL
Universita' Degli Studi Di Siena
Curated by ChEMBL
Affinity DataIC50: 151nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair