BDBM50029799 7-Methoxy-1-methyl-2,9-dihydro-1H-beta-carboline::7-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline::7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole::CHEMBL2089157::CHEMBL340807::HARMALINE
SMILES COc1ccc2c3CCN=C(C)c3[nH]c2c1
InChI Key InChIKey=RERZNCLIYCABFS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50029799
Affinity DataKi: 1.50E+3nMAssay Description:Binding affinity to 5-HT6R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT2A expressed in human HEK cells assessed as inhibition constant by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:Displacement of [3H]-citalopram from human 5-HT7 expressed in human HEK cells assessed as inhibition constant by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.40E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT2C expressed in human HEK cells assessed as inhibition constant by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT3R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT1DR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-mesulergine from human 5-HT1B expressed in human HEK cells assessed as inhibition constant by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT1A expressed in human HEK cells assessed as inhibition constant by FLIPR assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 5A receptor using LSD as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT5AR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
The University Of Tours
Curated by ChEMBL
The University Of Tours
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.37E+4nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Naresuan University
Curated by ChEMBL
Naresuan University
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of electric eel AChE using acetylcholine iodide as substrate measured every 5 sec for 2 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.04E+4nMAssay Description:Inhibition of snake venom BaP1 using Abz-Ala-Gly-Leu-Ala-Nba as substrate incubated for 30 mins prior to substrate addition by fluorescence spectroph...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity against rat brain Monoamine oxidase AMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+5nMAssay Description:In vitro inhibitory activity against rat brain Monoamine oxidase BMore data for this Ligand-Target Pair