BDBM50030117 (S)-2-Dimethylamino-3-(1H-indol-3-yl)-propionic acid 3,5-dimethyl-benzyl ester::2-Dimethylamino-3-(1H-indol-3-yl)-propionic acid 3,5-dimethyl-benzyl ester::CHEMBL23715

SMILES CN(C)[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(C)cc(C)c1

InChI Key InChIKey=SCUCGLNZVOAIMC-NRFANRHFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50030117   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030117((S)-2-Dimethylamino-3-(1H-indol-3-yl)-propionic ac...)
Affinity DataIC50:  553nMAssay Description:Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance PMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030117((S)-2-Dimethylamino-3-(1H-indol-3-yl)-propionic ac...)
Affinity DataIC50: >5.00E+3nMAssay Description:Affinity to NK3 receptors assayed by displacement of [125I]-Bolton-Hunter labeled eledoisin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030117((S)-2-Dimethylamino-3-(1H-indol-3-yl)-propionic ac...)
Affinity DataIC50:  550nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in CHO-expressed hNK1 using [125I]SP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030117((S)-2-Dimethylamino-3-(1H-indol-3-yl)-propionic ac...)
Affinity DataIC50:  553nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030117((S)-2-Dimethylamino-3-(1H-indol-3-yl)-propionic ac...)
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity to the NK2 receptor assayed by displacement of [125I]-Neurokinin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed