BDBM50030118 (S)-2-Ethylamino-3-(1H-indol-3-yl)-propionic acid benzyl ester::2-Ethylamino-3-(1H-indol-3-yl)-propionic acid benzyl ester::CHEMBL26623

SMILES CCN[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1

InChI Key InChIKey=UMNLNRHEUYRDHL-IBGZPJMESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50030118   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030118((S)-2-Ethylamino-3-(1H-indol-3-yl)-propionic acid ...)
Affinity DataIC50:  3.80E+3nMAssay Description:Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance PMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030118((S)-2-Ethylamino-3-(1H-indol-3-yl)-propionic acid ...)
Affinity DataIC50:  3.80E+3nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030118((S)-2-Ethylamino-3-(1H-indol-3-yl)-propionic acid ...)
Affinity DataIC50: >5.00E+3nMAssay Description:Affinity to NK3 receptors assayed by displacement of [125I]-Bolton-Hunter labeled eledoisin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030118((S)-2-Ethylamino-3-(1H-indol-3-yl)-propionic acid ...)
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity to the NK2 receptor assayed by displacement of [125I]-Neurokinin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed