BDBM50030127 (S)-2-Benzoylamino-3-(1H-indol-3-yl)-propionic acid 3,5-dimethyl-benzyl ester::CHEMBL278351

SMILES Cc1cc(C)cc(COC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccccc2)c1

InChI Key InChIKey=BKFSYSKVGGJRTB-VWLOTQADSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50030127   

TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030127((S)-2-Benzoylamino-3-(1H-indol-3-yl)-propionic aci...)
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity to the NK2 receptor assayed by displacement of [125I]-Neurokinin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030127((S)-2-Benzoylamino-3-(1H-indol-3-yl)-propionic aci...)
Affinity DataIC50: >5.00E+3nMAssay Description:Affinity to NK3 receptors assayed by displacement of [125I]-Bolton-Hunter labeled eledoisin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50030127((S)-2-Benzoylamino-3-(1H-indol-3-yl)-propionic aci...)
Affinity DataIC50:  21.9nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in CHO-expressed hNK1 using [125I]SP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50030127((S)-2-Benzoylamino-3-(1H-indol-3-yl)-propionic aci...)
Affinity DataIC50:  22nMAssay Description:Binding affinity against human Tachykinin receptor 1 expressed in CHO cells was measured by its ability to displace [125I]- Tyr-8 substance P.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50030127((S)-2-Benzoylamino-3-(1H-indol-3-yl)-propionic aci...)
Affinity DataIC50:  22nMAssay Description:Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance PMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed