BDBM50030510 CHEMBL299668::[1-Benzyl-7-chloro-1H-quinolin-(4E)-ylidene]-pentyl-amine
SMILES CCCCC\N=c1/ccn(Cc2ccccc2)c2cc(Cl)ccc12
InChI Key InChIKey=QCZNJMNZZBRTHD-BSYVCWPDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50030510
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Institute Of Nuclear Medicine
Curated by ChEMBL
Institute Of Nuclear Medicine
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Inhibition of rat brain voltage-gated sodium channel subunit alpha Nav1.2-mediated current expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Institute Of Nuclear Medicine
Curated by ChEMBL
Institute Of Nuclear Medicine
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human voltage-gated sodium channel subunit alpha Nav1.2 expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop
Curated by ChEMBL
Sanofi Winthrop
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Concentration inhibiting [125I]-ChTX (charybdotoxin) binding to N-type potassium channel.More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Sanofi Winthrop
Curated by ChEMBL
Sanofi Winthrop
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of outward potassium currents (IKn) in human T-lymphocyte N-type potassium channels.More data for this Ligand-Target Pair