BDBM50031515 CHEMBL3359142

SMILES Oc1ccc(cc1NC(=O)COc1ccccc1)C(=O)OCC#C

InChI Key InChIKey=FQUJUCMFSVMNTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50031515   

TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50031515(CHEMBL3359142)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of MDH2 (unknown origin) pre-incubated for 1 hr followed by malate and NAD+ additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50031515(CHEMBL3359142)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HIF-1alpha in human HCT116 cells incubated for 12 hrs under hypoxic conditions by Western blotting and HRE-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed