BDBM50031667 3-((10R,13S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-pyridine::CHEMBL310315

SMILES C[C@]12CCC3C(CC=C4C=CCC[C@]34C)C1CC=C2c1cccnc1

InChI Key InChIKey=LAZGFPQCCUTDPH-VYAPPMEMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031667   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50031667(3-((10R,13S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14...)
Affinity DataIC50:  5.60nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50031667(3-((10R,13S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human progesterone 17-alpha-hydroxylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50031667(3-((10R,13S)-10,13-Dimethyl-2,7,8,9,10,11,12,13,14...)
Affinity DataIC50:  13nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed