BDBM50031873 5-Chloro-6-[(2,5-dimethoxy-phenylamino)-methyl]-quinazoline-2,4-diamine::5-chloro-6-((2,5-dimethoxyphenylamino)methyl)quinazoline-2,4-diamine::CHEMBL88430
SMILES COc1ccc(OC)c(NCc2ccc3nc(N)nc(N)c3c2Cl)c1
InChI Key InChIKey=KEPKKUKRTDFXHZ-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50031873
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Concentration inhibiting T. gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Concentration inhibiting P. carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Concentration inhibiting rat liver dihydrofolate reductase .More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) of in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of Dihydrofolate reductase of Pneumocystis cariniiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Cryptosporidium hominis)
Dartmouth College
Curated by ChEMBL
Dartmouth College
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of Cryptosporidium hominis DHFRMore data for this Ligand-Target Pair