BDBM50033288 (2-Phenyl-quinazolin-4-yl)-thiophen-2-ylmethyl-amine::CHEMBL116890

SMILES C(Nc1nc(nc2ccccc12)-c1ccccc1)c1cccs1

InChI Key InChIKey=FVIAQILFHHNFFE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033288   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Biofor

Curated by ChEMBL
LigandPNGBDBM50033288((2-Phenyl-quinazolin-4-yl)-thiophen-2-ylmethyl-ami...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Homo sapiens)
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50033288((2-Phenyl-quinazolin-4-yl)-thiophen-2-ylmethyl-ami...)
Affinity DataIC50: <5.01E+4nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Homo sapiens (Human))
University Of Cambridge

Curated by ChEMBL
LigandPNGBDBM50033288((2-Phenyl-quinazolin-4-yl)-thiophen-2-ylmethyl-ami...)
Affinity DataIC50: <2.51E+4nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed