BDBM50033333 (3-Chloro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine; hydrochloride::CHEMBL1195084::CHEMBL553820

SMILES Clc1cccc(Nc2nc(nc3ccccc23)-c2ccccc2)c1

InChI Key InChIKey=FYOVPXMSRXGEEZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033333   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Biofor

Curated by ChEMBL
LigandPNGBDBM50033333((3-Chloro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50033333((3-Chloro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine...)
Affinity DataEC50:  11nMAssay Description:Activation of recombinant human ABCG2 ATPase activity expressed in baculovirus infected High five insect cell membranes after 20 mins by ascorbic aci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50033333((3-Chloro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine...)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells preincubated for 30 mins prior to Hoechst 33342 addition measured every 60 secs up to 120 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed