BDBM50033357 CHEMBL3357095

SMILES Fc1ccc(cc1)C1=C(COC1=O)c1ccccc1

InChI Key InChIKey=VKGMHNWSONUQEC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50033357   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033357(CHEMBL3357095)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033357(CHEMBL3357095)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of COX-2 in human 1483 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033357(CHEMBL3357095)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50033357(CHEMBL3357095)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of mouse COX-2 assessed as inhibition of [14C]arachidonic acid to radiolabeled prostaglandins preincubated for 15 mins by TLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed