BDBM50033927 (R)-2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanoic acid::CHEMBL6788

SMILES CCC[C@@H](NC(=O)c1ccc(cc1)N(CC#C)Cc1ccc2nc(C)[nH]c(=O)c2c1)C(O)=O

InChI Key InChIKey=GPDKHMRCUGYLOD-JOCHJYFZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033927   

TargetThymidylate synthase(Mus musculus)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033927((R)-2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6...)
Affinity DataIC50:  42nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed