BDBM50034261 5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-3-phenyl-5H-furan-2-one::CHEMBL10897

SMILES COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccccc2)cc1

InChI Key InChIKey=GCLJDQQEPIRTNF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50034261   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034261(5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl...)
Affinity DataIC50:  2.20E+3nMAssay Description:Antagonistic activity against human Endothelin A receptor expressed in LtKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034261(5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Tested for antagonistic activity against Endothelin A receptor in the rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034261(5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl...)
Affinity DataIC50: >2.50E+3nMAssay Description:Binding affinity against human cloned Endothelin B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034261(5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl...)
Affinity DataIC50:  2.20E+3nMAssay Description:Binding affinity against human cloned endothelin A receptor expressed in LTK-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034261(5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl...)
Affinity DataIC50: >2.50E+3nMAssay Description:Tested for antagonistic activity against Endothelin B receptor in the humans (CHO expressed).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed