BDBM50034417 4-Amino-N-[1,3,4]thiadiazol-2-yl-benzenesulfonamide::4-amino-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide::CHEMBL286737::US9320734, 100
SMILES Nc1ccc(cc1)S(=O)(=O)Nc1nncs1
InChI Key InChIKey=ATEAASNFYTUARU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50034417
TargetRAC-alpha serine/threonine-protein kinase(Mus musculus)
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of biotinylated phosphatidylinositol-3,4,5-phosphate from mouse AKT1 PH domain by surface plasmon resonance competitive binding assayMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKi: >5.00E+4nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 450nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...More data for this Ligand-Target Pair
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.70E+4nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The University Of Texas
Curated by ChEMBL
The University Of Texas
Curated by ChEMBL
Affinity DataKd: 450nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The University Of Texas
Curated by ChEMBL
The University Of Texas
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Akt phosphorylation in human BxPC3 cells by Western blottingMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataKd: 1.51E+4nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of AKT was measured by Western blotting using specific antibodies against phospho-Ser473-AKT in MiaPaCa-2 cells.Inhibition of AKT was meas...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase [1-123](Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph...More data for this Ligand-Target Pair