BDBM50034458 5-Isopropylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL416026
SMILES CC(C)Nc1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C
InChI Key InChIKey=IOVMJAOVAQFLLK-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50034458
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of [125I]-endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cellsMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair