BDBM50034475 5-(3-Phenyl-thioureido)-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL27063

SMILES Cc1noc(NS(=O)(=O)c2cccc3c(NC(=S)Nc4ccccc4)cccc23)c1C

InChI Key InChIKey=GSPSAYRFOXTOER-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034475   

TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034475(5-(3-Phenyl-thioureido)-naphthalene-1-sulfonic aci...)
Affinity DataIC50:  150nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed