BDBM50034503 (1R,2R)-3-((S)-Amino-carboxy-methyl)-cyclopropane-1,2-dicarboxylic acid::(1R,2R)-3-[(S)-amino(carboxy)methyl]cyclopropane-1,2-dicarboxylic acid::(2S,2'R,3'R)-2-(2',3')-dicarboxycyclopropylglycine::3-(Amino-carboxy-methyl)-cyclopropane-1,2-dicarboxylic acid::CHEMBL284193::DCG-IV

SMILES N[C@@H](C1[C@H]([C@@H]1C(O)=O)C(O)=O)C(O)=O

InChI Key InChIKey=MATPZHBYOVDBLI-JJYYJPOSSA-N

Data  9 KI  1 IC50  15 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50034503   

TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50034503((1R,2R)-3-((S)-Amino-carboxy-methyl)-cyclopropane-...)
Affinity DataEC50:  4.00E+4nMAssay Description:Metabotropic glutamate receptor 7 antagonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50034503((1R,2R)-3-((S)-Amino-carboxy-methyl)-cyclopropane-...)
Affinity DataEC50:  300nMAssay Description:Metabotropic glutamate receptor 2 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50034503((1R,2R)-3-((S)-Amino-carboxy-methyl)-cyclopropane-...)
Affinity DataEC50:  200nMAssay Description:Metabotropic glutamate receptor 3 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50034503((1R,2R)-3-((S)-Amino-carboxy-methyl)-cyclopropane-...)
Affinity DataEC50:  3.89E+5nMAssay Description:Metabotropic glutamate receptor 5 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50034503((1R,2R)-3-((S)-Amino-carboxy-methyl)-cyclopropane-...)
Affinity DataEC50:  2.30E+4nMAssay Description:Metabotropic glutamate receptor 4 antagonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50034503((1R,2R)-3-((S)-Amino-carboxy-methyl)-cyclopropane-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptor 1 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50034503((1R,2R)-3-((S)-Amino-carboxy-methyl)-cyclopropane-...)
Affinity DataEC50:  3.20E+4nMAssay Description:Metabotropic glutamate receptor 8 antagonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50034503((1R,2R)-3-((S)-Amino-carboxy-methyl)-cyclopropane-...)
Affinity DataEC50:  4.00E+4nMAssay Description:Metabotropic glutamate receptor 6 antagonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed