BDBM50034809 CHEMBL3338090
SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(CCNC2=O)n1CC(O)=O
InChI Key InChIKey=YCWLFLYOMFXNRF-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50034809
Affinity DataIC50: 6.5nMAssay Description:Antagonist activity at CRTh2 (unknown origin) stably expressed in CHO.K1 cells co-mixing the compound and PGD2 by radio-labelled [35S]-GTPgammaS bind...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 15 mins by radio-labelled [35S]-GTPga...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 30 mins by radio-labelled [35S]-GTPga...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 60 mins by radio-labelled [35S]-GTPga...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 180 mins by radio-labelled [35S]-GTPg...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by fluorescen...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at CRTh2 (unknown origin) stably expressed in CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgammaS binding assay ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 120 mins by radio-labelled [35S]-GTPg...More data for this Ligand-Target Pair