BDBM50035513 4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-N-pyridin-2-yl-benzamide::CHEMBL1775000::CHEMBL286607

SMILES COc1ccccc1N1CCN(CCN(C(=O)c2ccc(F)cc2)c2ccccn2)CC1

InChI Key InChIKey=YJZYDPRMWYWYCG-UHFFFAOYSA-N

Data  3 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50035513   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035513(4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  3.20nMAssay Description:In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50035513(4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of binding of [125I]8-OH-PIPAT ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Vu University Medical Center

Curated by ChEMBL
LigandPNGBDBM50035513(4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  151nMAssay Description:Binding affinity to alpha1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50035513(4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKd:  0.340nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed