BDBM50035620 CHEMBL3338445

SMILES COc1ccc(CNc2nc(OCc3ccccn3)ncc2C(=O)c2cc(OC)c(OC)c(OC)c2)cc1Cl

InChI Key InChIKey=DJVBNZMSHDWOSI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035620   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma

Curated by ChEMBL

LigandBDBM50035620(CHEMBL3338445)Copy SMILESCopy InChI

Affinity DataIC50:  0.130nMAssay Description:Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide methodMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))TBA

LigandBDBM50035620(CHEMBL3338445)Copy SMILESCopy InChI

Affinity DataIC50:  0.160nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails
Copy BDB DOI

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))TBA

LigandBDBM50035620(CHEMBL3338445)Copy SMILESCopy InChI

Affinity DataIC50:  280nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails
Copy BDB DOI