BDBM50035644 (6aR,12bR)-6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-9,10-diol::CHEMBL418791::Ro-21-7767

SMILES CN1Cc2ccccc2[C@H]2[C@H]1CCc1c(O)c(O)ccc21

InChI Key InChIKey=GFOJCADGVHYVJC-NVXWUHKLSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035644   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50035644((6aR,12bR)-6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo...)
Affinity DataIC50:  121nMAssay Description:Binding affinity for Dopamine receptor D2 was assessed in vitro in rat striatal membranes using [3H]-SCH- 23390 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50035644((6aR,12bR)-6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration was determined for the adenylate cyclase activity in rat striatal tissue as a measure of Dopamine receptor D1 functional acti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50035644((6aR,12bR)-6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo...)
Affinity DataIC50:  955nMAssay Description:Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed